Sexual health, even into older age, is important to many people. A new paper reports that older men with hypogonadism who take testosterone experience significant improvements in sexual activity, erectile function and libido. Testosterone therapy has long been a matter of interest (and controversy) for physicians, and this study is a landmark one that is worthy of further discussion.
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References
World Health Organization. Department of Reproductive Health and Research. Defining sexual health: Report of a technical consultation on sexual health, 28–31 January 2002, Geneva. [online], (2006).
Synder, P. J. et al. Effects of testosterone treatment in older men. N. Engl. J. Med. 347, 611–624 (2016).
Steidle, C. et al. AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function. J. Clin. Endocrinol. Metab. 88, 2673–2681 (2003).
Jain, P., Rademaker, A. W. & McVary, K. T. Testosterone supplementation for erectile dysfunction: results of a metaanalysis. J. Urol. 164, 371–375 (2000).
Page, S. T. et al. Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum. J. Clin. Endocrinol. Metab. 90, 1502–1510 (2005).
Basaria, S. et al. Adverse events associated with testosterone administration. N. Engl. J. Med. 363, 109–122 (2010).
US Food & Drug Administration. FDA drug safety communication: FDA cautions about using testosterone products for low testosterone due to aging; requires labeling change to inform of possible increased risk of heart attack and stroke with use. [online], (2014).
Kolata, G. Testosterone gel has modest benefits for men, study says. The New York Times [online], (2016).
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James Dupree declares contract grant support from Blue Cross Blue Shield of Michigan for his roles with the Michigan Value Collaborative and the Michigan Urologic Surgery Improvement Collaborative.
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Dupree, J. Testosterone therapy and sexual health in hypogonadal men. Nat Rev Urol 13, 244–245 (2016). https://doi.org/10.1038/nrurol.2016.66
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DOI: https://doi.org/10.1038/nrurol.2016.66