The HIV-1 Tat protein promotes viral transcription elongation by recruiting P-TEFb to RNA element TAR on the viral mRNA. Recent work from D'Orso and Frankel uncovers unexpected aspects of this process.
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Barboric, M., Lenasi, T. Kick-sTARting HIV-1 transcription elongation by 7SK snRNP deporTATion. Nat Struct Mol Biol 17, 928–930 (2010). https://doi.org/10.1038/nsmb0810-928
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DOI: https://doi.org/10.1038/nsmb0810-928
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