Abstract
An indirect technique of multiple weighing on an electronic balance inside an incubator was used to measure IWL in seven infants, 4-21 days old, receiving parenteral nutrition. Birth weight ranged from 960-1900 g (x̄ 1307±321g) and gestational age 26-32 weeks (x̄ 28.4±2 wks). Consecutive three hour Δ weight readings were made on each infant during infusion of four separate solutions while under the same environmental conditions and after allowing a 30-60 minute “washout” period between measurements. Intravenous fluids were infused at a rate of 7.7±1 ml/kg/ hour.
There was a highly significant correlation between caloric intake and insensible water loss. This indicates that (1) Parenteral nutrition solutions are rapidly metabolized and the increase in IWL is probably secondary to an elevated metabolic rate; (2) With increasing caloric intake, IWL may alter the fluid requirements of infants during parenteral nutrition.
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Marks, K., Farrell, T., Friedman, Z. et al. THE INFLUENCE OF HYPERALIMENTATION SOLUTIONS ON INSENSIBLE WATER LOSS (IWL) IN PREMATURE INFANTS. Pediatr Res 11, 446 (1977). https://doi.org/10.1203/00006450-197704000-00462
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DOI: https://doi.org/10.1203/00006450-197704000-00462