Abstract
Since an accelerated rate of placental transfer have been suggested for some trace elements as the gestation advances, determination of paired samples of maternal (M), umbilical cord arterial (A) and cord venous (V), serum zinc (Zn), iron (Fe), copper (Cu) and CP concentrations were carried out. The study group consisted of 10 healthy mothers and their full term newborn infants with gestational age of 38,6±1.4 wks and birth weight of 3219±133 gm. Comparison of serum concentrations of trace elements and CP on maternal-V, cord-V and cord-A follows:
Marked gradient favoring fetus in concentrations of Zn (1.8 fold) and Fe (3.5 fold), yet protecting it from high Cu transfer via placenta (1/3 rd of the mother's) are indicative of a well controlled active transport mechanism. Zn and Fe gradients observed here suggest that the fetus may deplete these two elements in the mother. The function of elevated maternal CP and Cu concentrations in serum and their relationship to Zn and Cu metabolism remain unknown.
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Foster, R., Chen, S., Ponce, E. et al. SERUM TRACE ELEMENTS AND CERULOPLASMIN (CP) CONCENTRATIONS ON MATERNAL AND CORD BLOOD AT DELIVERY. Pediatr Res 18 (Suppl 4), 196 (1984). https://doi.org/10.1203/00006450-198404001-00617
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DOI: https://doi.org/10.1203/00006450-198404001-00617