Abstract
Peripheral blood flow (PBF) depends on blood pressure (P), blood viscosity (1) and vascular hindrance (Z): PBF= P/R= P/(Zxn), where R is the peripheral resistance. Thus, blood transfusion can increase PBF by increasing P and decreasing Z and decrease PBF by increasing η. We have studied PBF (venous occlusion plethysmography), P (Doppler), blood volume (BV, Evans blue) and η (capillary viscometer) in 14 anemic neonates (gestational age 27-42 weeks) during the first week of life immediately before and after transfusion (Tx) of 20 ml of whole blood.
We conclude that Tx results in vasodilatation (decrease in Z) and increased pressure, theraby increasing blood flow in spite of increasing blood viscosity.
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Bauer, K., Versmold, H. & Linderkamp, O. 27 EFFECT OF BLOOD TRANSFUSION ON BLOOD VOLUME, BLOOD VISCOSITY AND PERIPHERAL CIRCULATION IN NEONATES. Pediatr Res 24, 265 (1988). https://doi.org/10.1203/00006450-198808000-00053
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DOI: https://doi.org/10.1203/00006450-198808000-00053