Abstract
We studied how a small change in dietary fat composition influences serum total and HDL cholesterol (CHL) in healthy infants between 7 and 13 mo of age in voluntary families (intervention group, N=21; controls, N=22). Families in the intervention group received intensive health education and individualized dietary advice at 1 to 3 mo intervals. The child's diet contained 37 E% fat, with saturated, mono- and polyunsaturated fats at 1:1:1 (controls 40 E% fat; 1,5:0,5:0,5). Serum CHL decreased in the intervention group from 4.3±0.4 at 7 mo to 3.9±0.5 mmol/l at 13 mo (P<0.05), but remained unchanged in the controls (4.2±0.6 at 7 mo, 4.1±0.6at 13 mo). Serum HDL CHL was stable in both groups. Apolipoprotein B decreased in the intervention group from 0,71±0,2 at 7 mo to 0,60±0,1 at 13 mo(n.s.). All children grew well. We conclude that a minor modification of dietary fat composition decreases cholesterolemia in infants without obvious side effects.
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Kovanen, H., Jokinen, E., Myyrinmaa, A. et al. 63 A CHANGE IN DIETARY FAT COMPOSITION IMPROVES SERUM CHOLESTEROL VALUES IN 7 TO 13 MONTH OLD INFANTS. Pediatr Res 30, 638 (1991). https://doi.org/10.1203/00006450-199112000-00093
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DOI: https://doi.org/10.1203/00006450-199112000-00093