Abstract
Between 1969 and 1992, 2,260 patients underwent surgery for pituitary adenomas, 95 (4.2%) of them before their 19th birthday. According to their endocrine activity, the majority of childhood tumors were endocrine active: PRL 38, ACTH (Cushing's) 35, GH 9, and ACTH (Nelson's) 4. As a group, patients treated for ACTPF-secreting tumors were the youngest (12.5 years). The recurrence rates varied with immunotype: PRL 2.6%, ACTH (Cushing's) 9%, endocrine inactive 9%, GH 22%, and ACTH (Nelson's) 0%. Surgical morbidity was minimal, and there were no serious complications or deaths. The distribution of immunotypes and recurrence rates differ from those in adults with pituitary adenomas.
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Wilson, C. PITUITARY ADENOMAS IN CHILDHOOD. Pediatr Res 33 (Suppl 5), S11 (1993). https://doi.org/10.1203/00006450-199305001-00048
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DOI: https://doi.org/10.1203/00006450-199305001-00048