Abstract
Objectives and study: Arthritis associated with inflammatory bowel diseases is mainly part of systemic sterile inflammation.
Authors studied occurrence of locomotive system's inflammation, by prospective and partly retrospective methods in 35 pediatric cases (17 boys and 18 girls) with inflammatory bowel disease (IBD), carried out in Pediatric Health Centre, Borsod-Abauj-County University Hospital, Miskolc, Hungary.
Methods: Data of patients history, physical (pediatric gastroenterologist, orthopedic surgeon), X-ray, and/ or ultrasound examinations were analized.
Results: Diagnosis of IBD was performed at 4.5- 17 years of age. Signs of locomotive system's inflammation appeared before, in same time, or after diagnosing bowel's inflammation. 9/35 (25.7%) patients presented knee-joint gout, swelling, synovial fluid production. 18/35 (50.3%) of them had migrating peripherial arthitis, 4/35 (11.4%) axial form. Transient rheumatic factor positivity appeared in 2/35 patients (5.5%). 29/35 pediatric IBD patients have some joint-mouvement system's complaints. Drugs of IBD therapy (nonsteroid antiinflammatory drugs, corticosteroids, azathioprin, biologics) were effective in associated arthritis also.
Conclusion: Antiinflammatory-immunesupressive drugs with systemic effect ease inflammation not only in bowel, but in joints also. It is important to consider joint inflammation when doctors propose therapy of patients with IBD.
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Szakos, E., Borbas, E., Huszanyik, I. et al. 792 Occurrence of Arthropaties in Children with Inflammatory Bowel Diseases. Pediatr Res 68 (Suppl 1), 400 (2010). https://doi.org/10.1203/00006450-201011001-00792
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DOI: https://doi.org/10.1203/00006450-201011001-00792