A humanized biomaterial microenvironment that mimics the pre-metastatic niche captures disseminated tumour cells and recapitulates metastatic progression after implantation in xenografted mice.
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Matei, I., Rampersaud, S. & Lyden, D. Engineered niches model the onset of metastasis. Nat Biomed Eng 2, 885–887 (2018). https://doi.org/10.1038/s41551-018-0326-7
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DOI: https://doi.org/10.1038/s41551-018-0326-7