As an intermediary between cells and scaffolding biomaterials, the extracellular matrix secreted by the cells offers challenges and opportunities for the design and fabrication of engineered tissues.
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Acknowledgements
U.B. acknowledges postdoctoral-funding support from the Balgrist University Hospital Zurich. M.M.S and E.G. acknowledge support from the UK Regenerative Medicine Platform ‘Acellular / Smart Materials – 3D Architecture’ (grant no. MR/R015651/1).
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Blache, U., Stevens, M.M. & Gentleman, E. Harnessing the secreted extracellular matrix to engineer tissues. Nat Biomed Eng 4, 357–363 (2020). https://doi.org/10.1038/s41551-019-0500-6
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DOI: https://doi.org/10.1038/s41551-019-0500-6
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