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XENO-ORGAN TRANSPLANTATION

Extensively edited pigs

Nature Biomedical Engineering volume 5, pages 128–129 (2021)Cite this article

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By using CRISPR and transposon constructs, pigs have been genetically modified to inactivate endogenous retroviruses and to enhance the compatibility of their organs with the human immune and coagulation systems.

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Fig. 1: Pigs for xeno-organ transplantation.

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Authors and Affiliations

  1. Chair of Livestock Biotechnology, Technical University of Munich, Freising, Germany

    Konrad Fischer & Angelika Schnieke

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  1. Konrad Fischer
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  2. Angelika Schnieke
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Correspondence to Angelika Schnieke.

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The authors declare no competing interests.

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Fischer, K., Schnieke, A. Extensively edited pigs. Nat Biomed Eng 5, 128–129 (2021). https://doi.org/10.1038/s41551-021-00684-2

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