In this issue of Nature Cell Biology, Mercier et al. show that acute changes in membrane tension may be a physiological trigger for ESCRT assembly, which drives membrane scission, luminal vesicle budding, and a wide array of other membrane remodelling events throughout the cell.
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References
Vietri, M., Radulovic, M. & Stenmark, H. Nat. Rev. Mol. Cell Biol. 21, 25–42 (2020).
McCullough, J., Frost, A. & Sundquist, W. I. Annu. Rev. Cell Dev. Biol. 34, 85–109 (2018).
Mercier, V. et al. Nat. Cell Biol. https://doi.org/10.1038/s41556-020-0546-4 (2020).
Lee, I. H., Kai, H., Carlson, L. A., Groves, J. T. & Hurley, J. H. Proc. Natl Acad. Sci. USA 112, 15892–15897 (2015).
Bertin, A. et al. Nat. Commun. 11, 2663 (2020).
Nepal, B., Sepehri, A. & Lazaridis, T. Protein Sci. 29, 1473–1485 (2020).
Colom, A. et al. Nat. Chem. 10, 1118–1125 (2018).
Caillat, C., Maity, S., Miguet, N., Roos, W. H. & Weissenhorn, W. Biochem. Soc. Trans. 47, 441–448 (2019).
White, I. J., Bailey, L. M., Aghakhani, M. R., Moss, S. E. & Futter, C. E. EMBO J. 25, 1–12 (2006).
Bright, N. A., Lindsay, M. R., Stewart, A. & Luzio, J. P. Traffic 2, 631–642 (2001).
Skowyra, M. L., Schlesinger, P. H., Naismith, T. V. & Hanson, P. I. Science 360, eaar5078 (2018).
Klumperman, J. & Raposo, G. Cold Spring Harb. Perspect. Biol. 6, a016857 (2014).
Baravalle, G. et al. Cell Tissue Res. 320, 99–113 (2005).
Falguières, T. et al. Mol. Biol. Cell 19, 4942–4955 (2008).
Kallay, L. M. et al. J. Biol. Chem. 286, 44067–44077 (2011).
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Piper, R.C. ESCRTs cut some slack. Nat Cell Biol 22, 915–916 (2020). https://doi.org/10.1038/s41556-020-0557-1
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DOI: https://doi.org/10.1038/s41556-020-0557-1