Three versatile and mutually orthogonal tRNA/aminoacyl-tRNA synthetase pairs have been developed. Collectively, these pairs enable the site-specific incorporation of three different non-canonical amino acids into a protein that can still be terminated faithfully by a natural stop codon.
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Change history
15 June 2020
In the originally published PDF version of this News & Views, Fig. 1 was missing codon labels ‘UAG’, ‘AGGA’ and ‘AGUA’. This has now been updated.
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Reinkemeier, C.D., Lemke, E.A. Raising the ribosomal repertoire. Nat. Chem. 12, 503–504 (2020). https://doi.org/10.1038/s41557-020-0476-6
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DOI: https://doi.org/10.1038/s41557-020-0476-6
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