Janus kinase (JAK) inhibitors have become standard treatment for patients with rheumatoid arthritis who do not respond well to other DMARDs. Concerns have been raised over an increased risk of venous thromboembolism with JAK inhibitors, tempering enthusiasm for their use in the clinic, but are these concerns justified?
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S.B.C. declares they have been a consultant and investigator for Abbvie, Eli Lilly, Gilead and Pfizer.
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Cohen, S.B. JAK inhibitors and VTE risk: how concerned should we be?. Nat Rev Rheumatol 17, 133–134 (2021). https://doi.org/10.1038/s41584-021-00575-5
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DOI: https://doi.org/10.1038/s41584-021-00575-5