Antimicrobial resistance in Neisseria gonorrhoeae compromises gonorrhoea treatment worldwide. Novel and optimized treatments and/or treatment strategies that effectively eradicate the infection with low selection of resistance are imperative. A new prospective clinical study provides further evidence that resistance-guided treatment of gonorrhoea with single-dose oral ciprofloxacin is efficacious in relevant settings and can reduce the selection pressure for resistance.
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Acknowledgements
Work at the WHO Collaborating Centre for Gonorrhoea and other STIs is supported by grants to M.U. from the WHO, Global Antibiotic Research and Development Partnership (GARDP), Research Committee of Örebro County and the Örebro University Hospital Foundation, Örebro, Sweden.
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Unemo, M. Optimizations to keep gonorrhoea treatable and reduce antimicrobial resistance selection. Nat Rev Urol 17, 609–610 (2020). https://doi.org/10.1038/s41585-020-00378-5
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DOI: https://doi.org/10.1038/s41585-020-00378-5