Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

AGING

Immunoprofiling comes of age

Nature Medicine volume 25, pages 362–364 (2019)Cite this article

Subjects

Application of immunoprofiling of human peripheral blood samples from an aging cohort identifies changes in the immune system that inform our understanding of age-associated complex diseases.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Identifying a measure of immune aging.

References

  1. Nikolich-Žugich, J. Nat. Immunol. 19, 10–19 (2018).

    Article  Google Scholar 

  2. Alpert, A. et al. Nat. Med. https://doi.org/10.1038/s41591-019-0381-y (2019).

  3. Libby, P. Nature 420, 868–874 (2002).

    Article  CAS  Google Scholar 

  4. Ridker, P. M. et al. N. Engl. J. Med. 377, 1119–1131 (2017).

    Article  CAS  Google Scholar 

  5. Ridker, P. M. et al. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa1809798 (2018).

  6. Bendall, S. C. et al. Science 332, 687–696 (2011).

    Article  CAS  Google Scholar 

  7. Stoeckius, M. et al. Nat. Methods 14, 865–868 (2017).

  8. Peterson, V. M.et al. Nat. Biotech. 35, 936–939 (2017).

  9. Fonseka, C. Y. et al. Sci. Transl. Med. 10, eaaq0305 (2018).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Center for Data Sciences, Brigham and Women’s Hospital, Boston, MA, USA

    Soumya Raychaudhuri

  2. Division of Rheumatology and Genetics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA

    Soumya Raychaudhuri

  3. Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA

    Soumya Raychaudhuri

  4. Broad Institute of Massachusetts Institute and Technology and Harvard University, Cambridge, MA, USA

    Soumya Raychaudhuri & Rajat M. Gupta

  5. Division of Rheumatology, Immunology, Allergy, Brigham and Women’s Hospital and Harvard Medical School, Brookline, MA, USA

    Soumya Raychaudhuri

  6. Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, The University of Manchester, Oxford Road, Manchester, UK

    Soumya Raychaudhuri

  7. Divisions of Cardiovascular Medicine and Genetics, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA

    Rajat M. Gupta

Authors
  1. Soumya Raychaudhuri
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rajat M. Gupta
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Soumya Raychaudhuri.

Ethics declarations

Competing interests

The authors declare no competing interests

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Raychaudhuri, S., Gupta, R.M. Immunoprofiling comes of age. Nat Med 25, 362–364 (2019). https://doi.org/10.1038/s41591-019-0387-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41591-019-0387-5

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing