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Cardiovascular disease

A protective smooth muscle cell transition in atherosclerosis

Nature Medicine volume 25, pages 1194–1195 (2019)Cite this article

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TCF21, a gene associated with coronary heart disease, promotes plaque stability and reduces clinical events by enhancing smooth muscle cell phenotype modulation into “fibromyocytes” in atherosclerosis.

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Fig. 1: The role of TCF21 in atherosclerosis.

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Authors and Affiliations

  1. Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA

    Huize Pan & Muredach P. Reilly

  2. Irving Institute for Clinical and Translational Research, Columbia University, New York, NY, USA

    Muredach P. Reilly

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  1. Huize Pan
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  2. Muredach P. Reilly
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Correspondence to Muredach P. Reilly.

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The authors declare no competing interests.

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Pan, H., Reilly, M.P. A protective smooth muscle cell transition in atherosclerosis. Nat Med 25, 1194–1195 (2019). https://doi.org/10.1038/s41591-019-0541-0

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