Following learning, memories for events are reorganized in a time-dependent manner in distributed hippocampal–cortical networks. While previous studies have focused on neural contributions to this process of systems consolidation, a new study by Kol et al. reveals that astrocytes play crucial modulatory roles in the formation of remote memories.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Spatial transcriptomics reveal neuron–astrocyte synergy in long-term memory
Nature Open Access 07 February 2024
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 /Â 30Â days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Volterra, A. & Meldolesi, J. Nat. Rev. Neurosci. 6, 626–640 (2005).
Adamsky, A. & Goshen, I. Neuroscience 370, 14–26 (2018).
Kol, A. et al. Nat. Neurosci. https://doi.org/10.1038/s41593-020-0679-6 (2020).
Haydon, P. G. Nat. Rev. Neurosci. 2, 185–193 (2001).
Josselyn, S. A., Köhler, S. & Frankland, P. W. Nat. Rev. Neurosci. 16, 521–534 (2015).
Gerlai, R., Wojtowicz, J. M., Marks, A. & Roder, J. Learn. Mem. 2, 26–39 (1995).
Adamsky, A. et al. Cell 174, 59–71.e14 (2018).
Frankland, P. W. & Bontempi, B. Nat. Rev. Neurosci. 6, 119–130 (2005).
Lesburguères, E. et al. Science 331, 924–928 (2011).
Kitamura, T. et al. Science 356, 73–78 (2017).
Rajasethupathy, P. et al. Nature 526, 653–659 (2015).
Santello, M., Toni, N. & Volterra, A. Nat. Neurosci. 22, 154–166 (2019).
Wang, C. et al. Science 367, 688–694 (2020).
Pan, S., Mayoral, S. R., Choi, H. S., Chan, J. R. & Kheirbek, M. A. Nat. Neurosci. 23, 487–499 (2020).
Steadman, P. E. et al. Neuron 105, 150–164.e6 (2020).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Frankland, P.W., Josselyn, S.A. Starring role for astrocytes in memory. Nat Neurosci 23, 1181–1182 (2020). https://doi.org/10.1038/s41593-020-0678-7
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41593-020-0678-7