Interorgan communication is emerging as a critical contributor to nutrient and energy homeostasis. A new study has identified a secreted liver factor that stimulates lipid synthesis in white adipose tissue and exacerbates obesity and insulin resistance.
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Kuang, H., Lin, J.D. GPNMB: expanding the code for liver–fat communication. Nat Metab 1, 507–508 (2019). https://doi.org/10.1038/s42255-019-0069-0
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DOI: https://doi.org/10.1038/s42255-019-0069-0
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