Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Ion channels are ubiquitously expressed in human tissues and represent one of the largest and best understood functional groups of proteins, with over 400 different types identified so far. Our understanding of their function is critical for the development of therapeutic approaches aimed at treating and preventing channelopathies, human diseases related to the dysfunction of ion channels. This Collection provides a home for research providing new directions for unravelling the molecular and genetic mechanisms of these pathologies.