Introducing GenomeNet-Architect, a neural architecture design framework that automatically optimises the overall layout of the architecture, the hyperparameters, and the training procedure of deep learning models for genome sequence data.

An fMRI study on a navigation task in multidimensional abstract spaces showed that the human hippocampus, entorhinal cortex, and orbitofrontal cortex collaborate in learning abstract space structures.

The fastest growing bacterium known is Vibrio natriegens. We have fused the two chromosomes of V. natriegens to create a single chromosome strain. Our results show that the bipartite genome is not a prerequisite for its rapid growth

The adaptor protein Disabled 2 (Dab2) regulates the activation and self-renewal of hair follicle stem cells via canonical Wnt pathway. Importantly, Dab2 is also involved in the ageing process.

Multiomic study reveals that tumor microenvironmental factors such as hypoxia influence intracellular infection of Fusobacterium nucleatum in colorectal cancer cells and provides clues to malignant transformation of infected cells.

Flexible interareal communication mechanism based on realistic spatiotemporal dynamics of propagating waves of neural population activity, showing how modulating this communication explains various neural effects of attention.

Comparison of the bone phenotypes of hyperthyroid versus euthyroid bone cell-specific conditional knockout mice suggests that the osteoblastic, but not osteoclast, BMP receptor BMPR1A is a main driver of hyperthyroidism-associated bone disease.

A study on global arthropod biodiversity dynamics reveals that beta-diversity increased with latitude, distance, and time. Species replacement and richness difference patterns vary across regions, supporting global biodiversity expectations.

A GWAS finds genetic link in ABCC9 gene affecting vocal pitch in both Mandarin and Icelandic speakers, suggesting a shared genetic influence on human vocal systems across populations.

Lipid droplet and palmitic acid accumulation in intervertebral disc degeneration nucleus pulposus cells drive endoplasmic reticulum stress-dependent cellular senescence.

This comment reports on work done at Harvard Medical School to identify areas for improvement in research rigor, reproducibility, and responsibility in pursuit of continued research excellence.

Documentation of women’s inclusion in Indian academia and conferences by BiasWatchIndia reveals the scale of underrepresentation of women across science, technology, engineering and mathematics.

In 2023, we conducted a virtual program to introduce early-career researchers to the fundamentals of academic journal editing. Here, we reflect on the mission of this program and its outcomes.

A comment article summarizing a range of research activities that contribute to understanding evolving Māori perspectives on Gene Editing and how they might contribute to future regulation.

Nanoparticle therapy continues to be an attractive avenue of targeted and personalised therapies. A molecular nano-conjugate developed by Zeng et al. effectively targets cancer cells and aids in their diagnosis, therapy, and also optimises innate immune responses.