a bat flying in a cave

Diversity in bat communities predicts coronavirus prevalence

Magdalena Meyer, Dominik Melville and colleagues study coronavirus infections in bats, and find that coronavirus prevalence is higher in less diverse bat communities.

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  • Understanding loss mechanisms in superconducting circuits is crucial for improving qubit coherence. Here the authors use a multimode resonator to study loss mechanisms in thin-film superconducting circuits and demonstrate on-chip quantum memories with lifetimes exceeding 1ms, using Ta thin-films and high-temperature substrate annealing

    • Suhas Ganjam
    • Yanhao Wang
    • Robert J. Schoelkopf
    ArticleOpen Access
  • Silicon-integrated graphene photodetectors exhibit promising bandwidths at telecom wavelengths, but their responsivity is usually limited. Here, the authors report the wafer-scale fabrication of waveguide-integrated detectors based on twisted bilayer graphene, showing responsivities up to 0.65 A/W and 3-dB bandwidths >65 GHz.

    • Qinci Wu
    • Jun Qian
    • Hailin Peng
    ArticleOpen Access
  • Magnetic tunnel junctions consist of two magnetic layers, separated by a thin insulator. The simplicity belies the industrial importance: magnetic tunnel junctions have a very wide variety of applications in contemporary society. Here, Fu et al present a magnetic tunnel junction composed of single van der Waals magnetic insulator, CrI3, exhibiting remarkably low power consumption.

    • ZhuangEn Fu
    • Piumi I. Samarawickrama
    • Jifa Tian
    ArticleOpen Access

Subjects within Physical sciences

Subjects within Earth and environmental sciences

  • Inactivation is an intrinsic property of NaV channel, but the mechanism for slow inactivation is not fully understood. Here, authors show a NaVEh structure in a potential slow-inactivated state, elucidating structural basis for slow inactivation.

    • Huiwen Chen
    • Zhanyi Xia
    • Daohua Jiang
    ArticleOpen Access
  • Several bottlenecks exist in metabolomics data analysis. Here, the authors present MetaboAnalystR 4.0 as a unified workflow for LC-MS untargeted metabolomics. It highlights significant improvements in LC-MS2 spectral processing and functional analysis, providing an end-to-end computational pipeline.

    • Zhiqiang Pang
    • Lei Xu
    • Jianguo Xia
    ArticleOpen Access
  • H9N2 avian influenza is a virus with zoonotic potential that is common in poultry in live bird markets in Asia. In this study, the authors use mathematical modelling to characterise transmission of H9N2 in live bird markets in Bangladesh and assess the effectiveness of potential interventions to reduce its circulation.

    • Francesco Pinotti
    • Lisa Kohnle
    • Guillaume Fournié
    ArticleOpen Access

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  • Developmental stress can detrimentally affect adult female reproductive behavior, influencing sexual receptivity and fertility. Recent work has demonstrated neuronal nitric oxide (NO) synthase (nNOS)-promoted NO release in the ventromedial hypothalamus as a nexus between pre-pubertal stress and adult sexual behavior in mice.

    • Konstantina Chachlaki
    CommentOpen Access
  • Cellular and organismal aging have been consistently associated with mitochondrial dysfunction and inflammation. Accumulating evidence indicates that aging-related inflammatory responses are mechanistically linked to compromised mitochondrial integrity coupled with mtDNA-driven CGAS activation, a process that is tonically inhibited by mitophagy.

    • Emma Guilbaud
    • Kristopher A. Sarosiek
    • Lorenzo Galluzzi
    CommentOpen Access
  • Dinoflagellates are ecologically important and essential to corals and other cnidarians as phytosymbionts, but their photosystems had been underexplored. Recently, photosystem I (PSI) of dinoflagellate Symbiodinium sp. was structurally characterized using cryo-Electron Microscopy (cryo-EM). These analyses revealed a distinct organization of the PSI supercomplex, including two previously unidentified subunits, PsaT and PsaU, and shed light on interactions between light harvesting antenna proteins and the PSI core. These results have implications with respect to the evolution of dinoflagellates and their association with cnidarians.

    • Senjie Lin
    • Shuaishuai Wu
    • Arthur R. Grossman
    CommentOpen Access
  • Arboviral infections are major public health threats, with 100 million people estimated to get sick annually from dengue infection alone. Globally, the risk of arboviruses is likely to further increase both within, and outside of, affected regions due to a combination of factors including climate change, human mobility, and other societal factors. Despite the availability of vaccines for some arbovirus infections, there is a lack of specific antiviral treatment options. Professor Johan Neyts at the University of Leuven, Belgium, has been working on developing antiviral strategies for more than 30 years. His current research focuses on developing antiviral drugs and vaccines against emerging and neglected viruses many of which are arboviruses. In this Q&A, he discusses the risks associated with vector-borne virus infections, challenges in developing efficient drugs for treatment, and current promising efforts to address these challenges.

    Q&AOpen Access
  • Multidisciplinary culture-dependent and -independent techniques elucidate the unique microbial nitrogen cycle in nutrient-poor coastal Antarctica soils and reveal the contribution of novel key microbes to their nitrogen budget.

    • Maximiliano Ortiz
    CommentOpen Access
  • Can many-body systems be beneficial to designing quantum technologies? We address this question by examining quantum engines, where recent studies indicate potential benefits through the harnessing of many-body effects, such as divergences close to phase transitions. However, open questions remain regarding their real-world applications.

    • Victor Mukherjee
    • Uma Divakaran
    CommentOpen Access
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