Browse Articles

Room temperature phosphorescent materials have many desirable properties, but fine control of these can be challenging. Here, the authors report a strategy for this control by dynamic lanthanide coordination in combination with organic phosphors.

This study presents an unprecedented analysis of agricultural land multi-degradation in 40 European countries, using twelve dataset-based processes that were modelled as land degradation convergence and combination pathways across the continent.

The inherent instability of poly(sulfur) renders the conversion of elementary sulfur into sulfur-rich polymers challenging which limits the use of this industrial by-product. Here, the authors demonstrate that inorganic sulfur can be utilized by copolymerizing with cyclic disulfides, producing high-performance thermoplastic elastomers with self-healing ability and degradability.

KtrAB complex is essential in K⁺ uptake for bacteria. Here authors illustrate the synergism of ATP and Na⁺ in activating K+ uptake of KtrAB from Bacillus subtilis and its gating mechanism, which may also shed light on other Na⁺-activated K⁺ channels.

Primaquine treatment for breastfeeding mothers is currently not recommended. Here, the authors develop a pharmacokinetic model to predict drug exposure of infants and show that ingesting breastmilk from mothers treated with primaquine results in <1% of maternal drug exposure. This suggests that primaquine should not be restricted in post-neonatal breastfeeding women as standard doses are unlikely to cause adverse events in infants.

The authors study a YbCoIn5/CeCoIn5/YbRhIn5 heterostructure. Using non-reciprocity in the second harmonic transport response, they demonstrate the existence of a specific form of finite-momentum pairing called a helical superconducting state, where the phase of the order parameter is spontaneously spatially modulated.

So far, only homoleptic N₂ complexes of silicon have been reported under matrix-isolation conditions including but the activation of more inert nitrogen by silylenes remains challenging. Here the authors report on the activation of dinitrogen by silylenes under cryogenic conditions.

Dual blockade therapy is currently being trialled for multiple tumour types, but efficacy is variable. Here, the authors use longitudinal proteomics profiling of 22 patients to develop a predictive model of therapy response.

Certain devices require rapid adhesion and detachment, but achieving both can be challenging. Here, the authors report the development of a supramolecular hydrogel with reversible tough adhesion and triggered photodetachment.

Using computer simulations authors identify the dynamic molecular motions controlling the structural conformation of the TWIK1 ion channel, showing that its ability to transport sodium upon acidification result from the evolution of the classical potassium-selective pore.

The knowledge gained from industrial catalysis benefits advancements of nanocatalytic medicines. Here the authors review the similarities, differences and connections in catalytic reactions between industrial and medical applications to support deep understanding and rational design of nanocatalytic medicines.

Soil-transmitted helminths (STHs) are major pathogens. Here the authors screen 480 structural families of natural products to find compounds that kill Caenorhabditis elegans specifically when they require rhodoquinone (RQ)-dependent metabolism: they identify several classes of compounds and show some compounds kill adult STHs.

Here, based on a systematic review and meta-analysis, the authors analyze the relationship between vaccine immunogenicity and vaccine protection against mpox and predict the durability of protection after vaccination. This helps inform the optimal vaccine deployment in a health emergency.

Single-cell manipulation and processing techniques and improvements in mass spectrometry sensitivity make single-cell proteomic profiling feasible. This study presents a label-free approach for the characterisation of native N-glycans of single mammalian cells and ng-level blood isolates, demonstrating the potential to detect cell surface glycome changes at the single-cell level in health or disease.

Multiplexed imaging to study cellular pathways can be hampered by lack of antibody specificity, especially when assessing signal activation. Here, the authors present Precise Emission Canceling Antibodies (PECAbs), which enable high-specificity sequential imaging and the study of signaling pathways.

The BHMbot provides an efficient running gait and a novel actuation mechanism for insect scale legged microrobots to solve the bottleneck problem of the severe running speed degradation after carrying essential payloads for untethered locomotion.

Plastics, chemical production, and fertilizers commonly rely on fossil fuels. Here the authors examine these uses in China and find that in 2017, 5%, 15%, and 7% of China’s total coal, crude oil, and natural gas were used as feedstocks in the chemical industry.

Cortico-entorhinal interactions remain poorly understood. Here, the authors demonstrate that a model of interacting networks predicts spontaneous persistent activity and inactivity in the medial, but not lateral, entorhinal cortex in vivo.

Experimental characterization of the transition state in chemical reactions is challenging due to its transient nature. Here, Zhang et al. observe quantum states near the activated complex region of the F + NH₃ → HF + NH₂ reaction via a dipole-bound state of the FNH₃^- anion formed upon photodetachment, which allows probing regions of reactive potential energy surfaces out of the Franck-Condon-active areas.

Here, the authors report the observation of an interlayer plasmon polaron in heterostructures composed of graphene and monolayer WS₂. This is manifested in the ARPES spectra as a strong quasiparticle peak accompanied by several carrier density-dependent shake-off replicas around the WS₂ conduction band minimum.