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The conversion between longitudinal heat flow and transverse charge current is a promising energy harvesting technology. Here, the authors show the large transverse thermoelectric effect induced by the mixed-dimensionality of Fermi surfaces.
Sleepwalking and related parasomnias are associated with partial awakenings out of non-rapid eye movement sleep. Here the authors show that when sleepwalkers have dream-like experiences during their episodes, they display brain activity patterns that resemble those previously described for dreams.
The role of subcellular thermogenesis during neuronal differentiation remains poorly understood. Here, the authors employ methods to monitor local intracellular temperature, and they investigate the effects of non-invasive temperature changes on cell differentiation using neuron-like cells.
Solid polymer electrolytes containing N,N-dimethylformamide (DMF) exhibit improved Li+ conductivity but poor cycle life due to incompatibility between the Li metal anode and DMF. Here, the authors report a polymer electrolyte composited with Hofmann-DMF complex that achieves both high Li+ conductivity and long cycle life.
When a solid object is placed in a supersaturated environment, it can exhibit interesting dynamics. Spagnolie et al. conducted an experiment using raisins and 3D-printed bodies in carbonated water and found that the motion of the solid object is influenced by the accumulation and release of bubbles as they reach the surface.
The NF-kB pathway is strictly regulated to prevent excessive inflammatory and immune responses. Here, Li et al. describe an alternative pathway of negative regulation of p65- driven gene expression.
The inherent chemical complexity in compositionally complex materials present a challenge in studying atomic diffusion. Here, the authors introduce a neural network kinetics scheme to effectively address this issue and reveal anomalous diffusion behavior in complex concentrated alloys.
The epitranscriptome holds many unexplored RNA functions, but detecting multiple modifications from one sample remains challenging. Here, authors devise a strategy combining AI and nanopore sequencing to uncover a transcriptome-wide co-occurrence of two modification types in individual RNA molecules.
Type 2 inflammation drives the formation of pathologic mucus in patients with asthma. Here, authors reveal a role for intelectin-1 in IL-13-induced mucus properties, and that an ITLN1 eQTL is associated with protection from the formation of mucus plugs in T2-high asthma.
Through neutron scattering experiments coupled with machine learning, the authors uncover the strong role of nuclear quantum effects in the dynamics of ammonia in both its solid and technologically relevant liquid phase.
By applying Hi-C to cells derived from the tumors of 24 GBM patients, the authors show pervasive structural variation in GBM chromosomal organization. How such patient-to-patient variation explains the characteristic gene expression patterns in each tumor is investigated.
Radiation-induced tumor vaccination is insufficient to elicit robust antitumor immune response. Here they combine chiral vidarabine monophosphate-gadolinium nanowires with immune checkpoint blockade therapy to synergistically induce antitumor immunity.
CALF-20 is a water stable structure capable of selectively separating CO2 from flue gas. Here authors use a close feedback loop between theory and experiments to understand CO2/water adsorption and framework flexibility of CALF-20.
The self-assembly of nanocrystals into checkerboard lattice patterns is difficult to control. Here, the authors investigate the formation of such patterns from hydrophilic/hydrophobic bifunctionalized Ag nanocubes and use multiscale simulations to understand the effects of physical forces.
Since the Jurassic, East European basins have likely been situated over a weakening mantle upwelling, which heated the basins and created suitable conditions for hydrocarbon maturation, according to geodata combined with modelling.
The authors present nonvolatile optical phase shift induced by ferroelectric hafnium zirconium oxide deposited on a SiN waveguide. This finding paves the way for largescale programmable photonic circuits for communication, computing, and sensing.
Aberrant signalling pathway activity is relevant for tumour growth and resistance to therapy, but remains hard to understand and target. Here, the authors develop VESPA, a phosphoproteomics-based machine learning algorithm that can elucidate response and adaptation to drug perturbations in cancer signalling pathways.
Room temperature phosphorescent materials have many desirable properties, but fine control of these can be challenging. Here, the authors report a strategy for this control by dynamic lanthanide coordination in combination with organic phosphors.