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Volume 6 Issue 6, June 2003

Eight photoreceptor neurons make up each individual ommatidium in the fly eye. Axons from these neurons target specific sites, called 'cartridges', in the brain. Zipursky and colleagues now report that flies with a non-functional mutant form of the cadherin-related cell surface protein Flamingo show disrupted patterning of photoreceptor axons to their targets. See page 557.

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  • Action potential propagation has been studied extensively in model networks. Now a new paper describes an innovative method of combining neuronal recordings with real-time neuronal modeling to create multi-layer feedforward networks. Neurons in deep layers tend to fire in synchrony, suggesting such networks may code sensory information by groups of neurons that fire together.

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  • Electrophysiological recordings coupled with genetic manipulations in fruit flies reveal activity patterns in the brain associated with the conspicuousness of visual objects, providing an elusive physiological link between gene products and behavior.

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  • Hippocampal neurons are thought to form a cognitive map of the environment based on multiple cues. A new study shows that young animals switch between cues more easily than aged animals and also perform better on a spatial learning task.

    • Emma R Wood
    • Paul A Dudchenko
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  • Neural activity in the enigmatic lateral intraparietal area (LIP) of the monkey brain is now reported to reflect the perceived direction of ambiguous motion more faithfully than does activity in other areas apparently specialized for motion analysis.

    • David A Leopold
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