Pharmacogenomics
Munir Pirmohamed reviews the pharmacogenomics field using examples of clinically relevant drug–gene associations, as well as the steps needed for implementing pharmacogenomics into clinical practice.
Munir Pirmohamed reviews the pharmacogenomics field using examples of clinically relevant drug–gene associations, as well as the steps needed for implementing pharmacogenomics into clinical practice.
Targeted genome modification using CRISPR–Cas genome editing, base editing or prime editing is driving base research in plants and precise molecular breeding. The authors review the technological principles underlying these methods, approaches for their delivery in plants, and emerging crop-breeding strategies based on targeted genome modification.