Disentangling channel gating mechanisms
Kalienkova et al. report structures of an FMRFamide-gated sodium channel (FaNaC) in several functional states, disentangling how different invertebrate receptors recognize similar neuropeptides.
Kalienkova et al. report structures of an FMRFamide-gated sodium channel (FaNaC) in several functional states, disentangling how different invertebrate receptors recognize similar neuropeptides.
Targeted biologics delivery requires programming multicomponent protein nanomaterials to enable selective targeting and response to environment changes in a single unified framework. A novel protein nanoparticle platform has been designed to modulate cell-surface target specificity, cargo packaging, and pH-dependent release of encapsulated cargo, providing exciting possibilities in biologics delivery.