Abstract
THE rosette test has been used extensively for the study of antibody forming cells1,2, but few data are available on rosette formation in unimmunized animals1,3. Most “spontaneous” rosette forming cells (RFC) in the spleens of unimmunized mice are small lymphocytes4 bearing immunoglobulin receptors5 specific for the antigen3; RFC against chicken erythrocytes are present before birth3. There is no correlation between the number of RFC in the spleen and the level of the corresponding humoral antibodies1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Biozzi, G., Stiffel, C., Mouton, D., Liacopoulos-Briot, M., Decreusefond, C., and Bouthillier, Y., Ann. Inst. Pasteur, 110, suppl. 3, 7 (1966).
Zaalberg, O. B., Nature, 202, 1231 (1964).
Laskov, R., Nature, 219, 973 (1968).
McConnell, I., Munro, A., Gurner, B. W., Coombs, R. R. A., Internat. Archs. Allergy App. Immunol., 35, 209 (1969).
Biozzi, G., Stiffel, C., Mouton, D., Bouthillier, Y., and Decreusefond, C., Immunology, 16, 349 (1969).
Bach, J. F., and Antoine, B., Nature, 217, 658 (1968).
Bach, J. F., Dardenne, M., Fournier, C., Nature, 222, 998 (1969).
Raff, M., Nature, 224, 378 (1969).
Bach, J. F., Dardenne, M., CR Acad. Sci., Paris, 269, 751 (1969).
Harris, R., and Ukaejiofo, E. O., Lancet, ii, 327 (1969).
Santos, G. W., and Owens, jun., A. H., Fed. Proc., 27, 506 (1968).
Burnet, F. M., Cellular Immunology (Melbourne University Press, 1969).
Wigzell, H., and Makela, O., J. Exp. Med. (in the press).
Ada, G. L., and Byrt, P., Nature, 222, 1291 (1969).
Bach, J. F., Lancet, i, 565 (1970).
Bach, J. F., Dardenne, M., Dormont, J., and Antoine, B., Transpl. Proc. 1, 403 (1969).
Bach, J. F., Dormont, J., Dardenne, M., and Balner, H., Transplantation, 8, 265 (1969).
Dwyer, J. M., and Mackay, I. R., Lancet, i, 164 (1970).
Brain, P., Gordon, J., and Willets, W. A., Clin. Exp. Immunol., 6, 681 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BACH, JF., MULLER, JY. & DARDENNE, M. In vivo Specific Antigen Recognition by Rosette Forming Cells. Nature 227, 1251–1252 (1970). https://doi.org/10.1038/2271251a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/2271251a0
This article is cited by
-
Antigenic response in the presence of high levels of angiogenin
Bulletin of Experimental Biology and Medicine (1997)
-
Increased number of precursors of rosette-forming cells sensitive to thymus hormone in the spleen of mice vaccinated with smallpox vaccine
Bulletin of Experimental Biology and Medicine (1978)
-
Percent distribution of T- and B-cells in tonsils of children, juveniles and adults
Archives of Oto-Rhino-Laryngology (1977)
-
Thymus-dependent Functions of Mouse Thymocyte-Fibroblast Hybrid Cells
Nature New Biology (1973)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
