Abstract
Replying to: T. Barkman & J. Zhang Nature 462, 10.1038/nature08663 (2009)
Barkman and Zhang1 level two criticisms at our report of escape from adaptive conflict (EAC)2. The first criticism is that our evidence of repeated adaptive substitution in the DFR-A/C lineage is consistent with either EAC or neofunctionalization in that lineage. As indicated in our original report2, we do not disagree with this claim, but believe it misses the point that the hallmark of EAC is the adaptive improvement of function in both duplicate lineages. The repeated positive selection in the DFR-A/C lineage simply demonstrates improvement of some as yet unspecified function in that lineage.
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References
Barkman, T. & Zhang, J. Evidence for escape from adaptive conflict? Nature 462 10.1038/nature08663 (2009)
Des Marais, D. L. & Rausher, M. D. Escape from adaptive conflict after duplication in an anthocyanin pathway gene. Nature 454, 762–765 (2008)
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Des Marais, D., Rausher, M. Des Marais & Rausher reply . Nature 462, E2–E3 (2009). https://doi.org/10.1038/nature08664
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DOI: https://doi.org/10.1038/nature08664
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