Abstract
The guanine-nucleotide-exchange factor Cdc24 is a critical regulator of cell polarity. Far1 is a key player in Cdc24 regulation, controlling Cdc24 activity in budding yeast by regulating its subcellular localization in response to two very different signals — one external and one internal.
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References
Chant, J. Annu. Rev. Cell Dev. Biol. 15, 365– 391 (1999).
Hall, A. Science 279, 509–514 ( 1998).
Shimada, Y., Gulli, M.-P. & Peter, M. Nature Cell Biol. 2, 117– 124 (2000).
Butty, A.-C., Pryciak, P., Huang, L. S., Herskowitz, I. & Peter, M. Science 282, 1511–1516 (1998).
Nern, A. & Arkowitz, R. A. J. Cell Biol. 144 , 1187–1202 (1999).
Valtz, N., Peter, M. & Herskowitz, I. J. Cell Biol. 131, 863– 873 (1995).
Nern, A. & Arkowitz, R. A. Nature 391, 195–198 (1998).
Toenjes, K. A., Sawyer, M. M. & Johnson, D. I. Curr. Biol. 9, 1183– 1186 (1999).
Henchoz, S. et al. Genes Dev. 11, 3046– 3060 (1997).
Blondel, M. et al. Genes Dev. 13, 2284–2300 (1999).
Peter, M. & Herskowitz, I. Science 265, 1228–1231 (1994).
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O’Shea, E., Herskowitz, I. The ins and outs of cell-polarity decisions. Nat Cell Biol 2, E39–E40 (2000). https://doi.org/10.1038/35004065
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DOI: https://doi.org/10.1038/35004065
