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Multiple routes to similar network output

Nature Neuroscience volume 7, pages 1287–1288 (2004)Cite this article

Neuronal networks are built from neurons with different properties and from synapses of different strengths. Modeling suggests that networks can tune these parameters to many different combinations that nonetheless produce very similar network outputs.

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Figure 1: Example illustrating how different combinations of synaptic strength and intrinsic neuron properties could produce outputs that have the same cycle period, spike number and phase relationships (albeit with fine differences in action potential timing and slow-wave trajectories).

References

  1. Golowasch, J., Abbott, L. & Marder, E. J. Neurosci. 19, RC33 (1999).

    Article  CAS  Google Scholar 

  2. Goldman, M., Golowasch, J., Marder, E. & Abbott, L. J. Neurosci. 21, 5229–5238 (2001).

    Article  CAS  Google Scholar 

  3. Golowasch, J., Goldman, M., Abbott, L. & Marder, E. J. Neurophysiol. 87, 1129–1131 (2002).

    Article  Google Scholar 

  4. Prinz, A., Billimoria, C. & Marder, E. J. Neurophysiol. 90, 3998–4015 (2003).

    Article  Google Scholar 

  5. Prinz, A., Bucher, D. & Marder, E. Nat. Neurosci. 7, 1345–1352 (2004).

    Article  CAS  Google Scholar 

  6. Johnson, B., Peck, J. & Harris-Warrick, R. J. Neurophysiol. 74, 437–452 (1995).

    Article  CAS  Google Scholar 

  7. Johnson, B., Peck, J. & Harris-Warrick, R. J. Exp. Biol. 156, 267–285 (1991).

    CAS  PubMed  Google Scholar 

  8. Liu, Z., Golowasch, J., Marder, E. & Abbott, L. J. Neurosci. 18, 2309–2320 (1998).

    Article  CAS  Google Scholar 

  9. LeMasson, G., Marder, E. & Abbott, L. Science 259, 1915–1917 (1993).

    Article  CAS  Google Scholar 

Download references

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  1. The author is in the Department of Biological Sciences, Ohio University, Athens, 45701, Ohio, USA

    Scott L Hooper

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  1. Scott L Hooper
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Hooper, S. Multiple routes to similar network output. Nat Neurosci 7, 1287–1288 (2004). https://doi.org/10.1038/nn1204-1287

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