Table 3 Genetic correlation (ρg) of adiposity traits with apnea hypopnea index

From: Shared genetic basis for obstructive sleep apnea and adiposity measures

 

Home sample

GCRC sample

GCRC sample with BMI adjustment

 

ρg

H0: ρg=0

H0: ρg=1

ρg

H0: ρg=0

H0: ρg=1

ρg

H0: ρg=0

H0: ρg=1

Body mass index

0.59 (0.06)

P<10−10

P<10−10

0.64 (0.09)

P<10−5

P<10−5

Waist

0.61 (0.06)

P<10−10

P<10−10

0.67 (0.09)

P<10−5

P<10−4

0.22 (0.18)

P=0.22

P<10−4

Hip

0.57 (0.06)

P<10−10

P<10−10

0.61 (0.10)

P<10−5

P<10−5

−0.06 (0.19)

P=0.77

P<10−5

Neck

0.59 (0.06)

P<10−10

P<10−10

0.56 (0.10)

P<10−4

P<10−6

0.05 (0.16)

P=0.73

P<10−5

Leptin

   

0.46 (0.16)

P=0.015

P<10−3

−0.43 (0.36)

P=0.20

P=0.80

Adiponectin

   

−0.34 (0.13)

P=0.012

P<10−7

−0.15 (0.15)

P=0.32

P<10−5

Resistin

   

0.11 (0.13)

P=0.41

P<10−7

0.01 (0.14)

P=0.92

P<10−5

  1. Abbreviations: BMI, body mass index; GCRC, general clinical research center; ρg, genetic correlation.
  2. Maximum likelihood estimates are displayed with standard errors in parentheses.
  3. All models include age, age2, sex, age × sex and height as covariates.