Figure 6
Cell cycle profiles of hKn cells treated under various conditions. HKn cells were transfected with no oligonucleotide, 300 nM Bcl-xL antisense inhibitor (ISIS 16009), or 300 nM control (ISIS 20292) oligonucleotide. Twenty-four hours after transfection, cells were treated with 100 mJ/m2 of UV-B radiation or left untreated. Twenty-four hours after UV-B treatment, cells were analysed for apoptosis as described in the Materials and methods. The percent gated population represents the cells that are hypochromatic due to chromatin condensation and contain sub-diploid content DNA (% apoptotic cells)
