Abstract
DR. RIMINGTON has no new point to raise. Originally, he had two difficulties, one of which has apparently been eliminated by my reply to his earlier communication. As regards the second, his difficulty has been reduced to a doubt whether re-determination of the glutamic and aspartic acid content of wool will give a sufficient increase to account precisely for the amide nitrogen as well as arginine and lysine. Even this doubt must disappear in the light of Jones and Moeller's 1 determinations of aspartic and glutamic acids in various proteins. These authors state that “new determinations of these amino acids have been made in a number of typical proteins, and invariably higher results for aspartic acid were obtained than those previously obtained by the ester method. In several cases from 4 to 9 times as much was found.”
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References
Jones and Moeller, J. Biol. Chem., 79, 429; 1928.
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SPEAKMAN, J. Constitution of the Keratin Molecule. Nature 130, 401 (1932). https://doi.org/10.1038/130401b0
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DOI: https://doi.org/10.1038/130401b0
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