Table 2 Clinical grading values of face, hand and décolletage in post-menopausal women before and after supplementation with dietary supplement or placebo for 2, 3 and 6 months
From: Effect of a novel dietary supplement on skin aging in post-menopausal women
Active group (n=38) | Placebo group (n=42) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Baseline | Month 2 | Month 3 | Month 6 | Baseline | Month 2 | Month 3 | Month 6 | ANOVA P-value a | |
Face | |||||||||
Forehead wrinkles | 4.4±0.3b | 4.3±0.3 | 4.1±0.3 | 4.0±0.3 | 4.7±0.4 | 4.6±0.4 | 4.5±0.3 | 4.6±0.3 | 0.01c |
Periocular wrinkles | 5.4±0.2 | 5.0±0.2 | 4.7±0.2 | 4.6±0.2 | 5.4±0.2 | 5.1±0.2 | 4.8±0.2 | 4.9±0.2 | 0.02c |
Perioral fine wrinkles | 5.1±0.3 | 5.0±0.3 | 4.7±0.3 | 4.5±0.3 | 5.2±0.3 | 5.1±0.2 | 4.9±0.3 | 4.9±0.3 | 0.01c |
Mottled hyper pigmentation | 4.6±0.2 | 4.4±0.2 | 4.1±0.2 | 3.9±0.2 | 4.8±0.2 | 4.6±0.2 | 4.4±0.2 | 4.4±0.2 | <0.01c |
Tactile roughness | 2.2±0.2 | 1.2±0.2 | 0.7±0.1 | 0.5±0.1 | 2.8±0.2 | 1.7±0.2 | 1.1±0.2 | 1.1±0.2 | NS |
Laxity | 4.9±0.2 | 4.8±0.2 | 4.2±0.2 | 4.0±0.2 | 4.8±0.2 | 4.7±0.2 | 4.3±0.2 | 4.2±0.2 | 0.01c |
Sagging | 4.8±0.2 | 4.7±0.2 | 4.4±0.2 | 4.2±0.2 | 4.9±0.2 | 4.9±0.2 | 4.6±0.2 | 4.6±0.2 | 0.01c |
Teleangiectasia | 2.7±0.3 | 2.6±0.3 | 2.4±0.3 | 2.3±0.2 | 3.6±0.3 | 3.6±0.3 | 3.4±0.3 | 3.4±0.3 | NS |
Under eye dark circles | 2.6±0.2 | 2.4±0.2 | 2.1±0.2 | 2.1±0.2 | 2.5±0.2 | 2.4±0.2 | 2.3±0.2 | 2.3±0.2 | 0.01c |
Overall facial appearance | 5.3±0.2 | 5.1±0.2 | 4.8±0.2 | 4.5±0.2 | 5.5±0.2 | 5.2±0.2 | 5.0±0.2 | 5.1±0.2 | <0.01c |
Decollétage | |||||||||
Crepyness | 3.7±0.2 | 3.6±0.2d | 3.4±0.2d | 3.4±0.2 | 3.7±0.1 | 3.7±0.2 | 3.7±0.2 | 3.7±0.2 | <0.01c |
Mottled hyper pigmentation | 5.0±0.2 | 4.9±0.2 | 4.6±0.2 | 4.6±0.2 | 5.1±0.2 | 5.0±0.2 | 4.8±0.2 | 4.9±0.2 | NS |
Overall appearance | 5.0±0.2 | 4.9±0.2 | 4.6±0.2d | 4.5±0.2 | 5.0±0.2 | 5.0±0.2 | 4.9±0.2 | 5.0±0.2 | <0.01c |
Hand | |||||||||
Crepyness | 4.9±0.2 | 4.6±0.3 | 4.1±0.3d | 4.0±0.3 | 5.4±0.3 | 5.2±0.3 | 4.9±0.3 | 4.9±0.3 | <0.01c |
Thinnness | 4.4±0.3 | 4.2±0.3 | 3.9±0.3 | 3.8±0.3 | 4.6±0.4 | 4.5±0.3 | 4.3±0.3 | 4.3±0.3 | NS |
Mottled hyper pigmentation | 4.7±0.2 | 4.0±0.3 | 3.4±0.3d | 3.3±0.3 | 4.9±0.3 | 4.4±0.3 | 4.0±0.3 | 3.9±0.3 | NS |
Pinch recoil | 2.6±0.1 | 2.4±0.1 | 2.3±0.1 | 2.1±0.1 | 2.8±0.1 | 2.6±0.1 | 2.3±0.1 | 2.4±0.1 | NS |
