Table 3 Ultrasound density of crow's foot area and grading values of digital photographic images of face in post-menopausal women before and after supplementation with dietary supplement or placebo for 2, 3 and 6 months

From: Effect of a novel dietary supplement on skin aging in post-menopausal women

 

Active group (n=38)

Placebo group (n=42)

 

Baseline

Month 2

Month 3

Month 6

Baseline

Month 2

Month 3

Month 6

ANOVA P-value a

Face

 Forehead wrinkles

4.2±0.2b

4.1±0.3

3.9±0.2c

3.9±0.2

4.2±0.2

4.2±0.2

4.1±0.2

4.2±0.2

<0.01d

 Periocular wrinkles

5.0±0.2

4.8±0.2

4.5±0.2

4.4±0.2

5.0±0.2

4.9±0.2

4.8±0.2

4.8±0.2

<0.01d

 Perioral fine wrinkles

5.0±0.3

4.9±0.3

4.8±0.3

4.9±0.3

4.9±0.2

4.9±0.2

4.7±0.2

4.8±0.2

NS

 Mottled hyper pigmentation

4.5±0.2

4.3±0.2

4.1±0.2c

3.9±0.2

4.7±0.2

4.6±0.2

4.4±0.2

4.5±0.2

<0.01d

 Teleangiectasia

1.0±0.3

0.9±0.2

0.9±0.2

0.7±0.2

1.6±0.3

1.4±0.3

1.5±0.3

1.5±0.3

NS

 Under eye dark circles

2.4±0.3

2.3±0.3

2.2±0.3c

2.2±0.3

2.8±0.3

2.7±0.3

2.8±0.3

2.7±0.3

NS

 Overall appearance

5.5±0.1

5.2±0.1

4.9±0.1c

4.9±0.2

5.7±0.2

5.5±0.1

5.4±0.2

5.4±0.2

<0.01d

Crow's foot area

 Ultra sound density

41.7±1.1

44.5±1.0

45.8±1.0

49.9±1.0

40.7±0.8

44.2±0.8

46.7±0.9

44.1±0.8

<0.01d

  1. aSignificant difference between active group and placebo at month 6.
  2. bMean values±s.e.m.
  3. cSignificant difference between active group and placebo (P<0.05).
  4. dSignificant difference between active group and placebo at month 6.