Table 3 Influence of long-term pre- and/or probiotic administration on faecal β-glucuronidase and β-glucosidase enzyme activity (mg product formed/g faeces/h), total FO and FDW in groups 1, 2 and 3

From: Effect of dietary intervention with different pre- and probiotics on intestinal bacterial enzyme activities

 

Enzyme

Baseline

Treatment a

   

Period 1

Period 2

Period 3

Group 1

β-Glucuronidase

0.84±0.32

0.47±0.28b

0.73±0.20

0.77±0.28

 

β-Glucosidase

0.97±0.65

0.98±0.48

0.85±0.46

0.89±0.62

 

FDW (%)

26.62±6.12

25.37±9.20

25.96±7.44

22.39±6.90

 

FO (g/72 h)

234±98

196±79

241±119

199±67

Group 2

β-Glucuronidase

0.61±0.31

0.45±0.20

0.56±0.25

0.59±0.33

 

β-Glucosidase

0.99±0.78

0.99±0.87

1.12±0.79

0.88±0.49

 

FDW (%)

24.60±4.52

21.90±6.71

25.64±3.16

23.58±5.42

 

FO (g/72 h)

387±138

387±138

305±87

381±233

Group 3

β-Glucuronidase

0.63±0.16

0.53±0.31

0.49±0.39

0.65±0.22

 

β-Glucosidase

1.23±0.64

1.15±0.78

0.93±0.54

1.03±0.60

 

FDW (%)

22.78±4.56

22.69±6.24

20.36±4.93

23.39±5.34

 

FO (g/72 h)

334±137

377±107

337±177

291±170

  1. Abbreviations: FDW, faecal dry weight; FO, faecal output; s.d., standard deviation.
  2. Mean±s.d., Wilcoxon test, α=0.05.
  3. aGroups 1 and 2: period 1: prebiotic lactulose; period 2: placebo; period 3: probiotic S. boulardii. Group 3: period 1: prebiotic lactulose; period 2: synbiotic lactulose+S. boulardii; period 3: probiotic S. boulardii.
  4. bSignificantly different from baseline: P=0.007.