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A Reaction of D-Glucosamine in the Presence of ‘Dry’ Protein

Abstract

IN work on the reaction of reducing sugars with proteins in the ‘dry’ state already reported1, glucosamine (2-amino-D-glucose) was used as an aldo hexose modified at the important carbon 2 position. Browning of the reaction mixture was found to occur extremely rapidly; but the chemical data indicated that something quite different from the normal protein amino group – sugar aldehyde group type of condensation2 was taking place.

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References

  1. Lea, C. H., and Rhodes, D. N., Biochim. Biophys. Acta (in the press).

  2. Lea, C. H., and Hannan, R. S., Biochim. Biophys. Acta, 3, 313 (1949); Biochem. J., 47, 626 (1950). Schwartz, H. M., and Lea, C. H., Biochem. J., [50, 713 (1952)].

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LEA, C., RHODES, D. & BORRELL, S. A Reaction of D-Glucosamine in the Presence of ‘Dry’ Protein. Nature 169, 1097–1098 (1952). https://doi.org/10.1038/1691097a0

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