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Normal Donor Follow-up

Impact of stem cell donation modality on normal donor quality of life: a prospective randomized study

Bone Marrow Transplantation volume 31, pages 1033–1035 (2003)Cite this article

Summary:

As part of a previously reported trial comparing granulocyte-colony stimulating factor (G-CSF) stimulated bone marrow and peripheral blood stem cells (PBSCs) in allogeneic stem cell transplantation, we included a questionnaire to compare donor morbidity and long-term complications between the two donation procedures. Bone marrow donation was associated with significantly more donors experiencing localized pain at the donation site compared to PBSC collection. However, this was not associated with any increased delay in returning to normal activity. Although a minority of bone marrow donors suffered chronic pain at the donation site, no serious long-term side effects relating to G-CSF stimulated stem cell donation were identified.

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Authors and Affiliations

  1. Department of Haematology, Royal Brisbane Hospital, Brisbane, Australia

    G A Kennedy, J Morton, R Western, J Butler, J Daly & S Durrant

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  1. G A Kennedy
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  2. J Morton
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  3. R Western
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  4. J Butler
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  5. J Daly
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  6. S Durrant
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Kennedy, G., Morton, J., Western, R. et al. Impact of stem cell donation modality on normal donor quality of life: a prospective randomized study. Bone Marrow Transplant 31, 1033–1035 (2003). https://doi.org/10.1038/sj.bmt.1704053

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