This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Ferrara JL, Deeg HJ . Graft-versus-host disease. N Engl J Med 1991; 324: 667–674.
Hori T . Roles of OX40 in the pathogenesis and the control of diseases. Int J Hematol 2006; 83: 17–22.
Tittle TV, Weinberg AD, Steinkeler CN, Maziarz RT . Expression of the T-cell activation antigen, OX-40, identifies alloreactive T cells in acute graft-versus-host disease. Blood 1997; 89: 4652–4658.
Kotani A, Ishikawa T, Matsumura Y, Ichinohe T, Ohno H, Hori T et al. Correlation of peripheral blood OX40+(CD134+) T cells with chronic graft-versus-host disease in patients who underwent allogeneic hematopoietic stem cell transplantation. Blood 2001; 98: 3162–3164.
Matsumura Y, Hori T, Nishigori C, Shirogane K, Toda KI, Uchiyama T et al. Expression of CD134 and CD134 ligand in lesional and nonlesional psoriatic skin. Arch Dermatol Res 2003; 294: 563–566.
Canninga-van Dijk MR, Sanders CJ, Verdonck LF, Fijnheer R, van den Tweel JG . Differential diagnosis of skin lesions after allogeneic haematopoietic stem cell transplantation. Histopathology 2003; 42: 313–330.
Kashiwakura J, Yokoi H, Saito H, Okayama Y . T cell proliferation by direct cross-talk between OX40 ligand on human mast cells and OX40 on human T cells: comparison of gene expression profiles between human tonsillar and lung-cultured mast cells. J Immunol 2004; 173: 5247–5257.
Galli SJ, Nakae S, Tsai M . Mast cells in the development of adaptive immune responses. Nat Immunol 2005; 6: 135–142.
Henz BM, Maurer M, Lippert U, Worm M, Babina M . Mast cells as initiators of immunity and host defense. Exp Dermatol 2001; 10: 1–10.
Zweifel M, Hirsiger H, Matozan K, Welle M, Schaffner T, Mohacsi P . Mast cells in ongoing acute rejection: increase in number and expression of a different phenotype in rat heart transplants. Transplantation 2002; 73: 1707–1716.
Acknowledgements
This work was partly supported by the grants-in-aid from the Ministry of Education, Culture, Sports, Science and Technology of Japan. We thank Dr H Shimada (Shizuoka General Hospital) for his cooperation in collecting the skin samples and Dr T Shirase (Laboratory of Anatomic Pathology, Kyoto University) for the useful advice from pathological point of view. We also thank Dr M Hishizawa for his experimental support and Ms K Fukunaga (Department of Hematology and Oncology, Kyoto University) for technical assistance.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kotani, A., Hori, T., Fujita, T. et al. Involvement of OX40 ligand+ mast cells in chronic GVHD after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant 39, 373–375 (2007). https://doi.org/10.1038/sj.bmt.1705587
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.bmt.1705587
This article is cited by
-
T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword
Nature Reviews Cardiology (2019)
-
Natural OX40L expressed on human T cell leukemia virus type-I-immortalized T cell lines interferes with infection of activated peripheral blood mononuclear cells by CCR5-utilizing human immunodeficiency virus
Virology Journal (2013)