Abstract
DURING the course of studies on the synthesis of sulphate esters an opportunity was taken to obtain evidence to support the suggestion1 that the type II mammalian arylsulphatases (arylsulphatases A and B)2 were unlikely to be directly involved in the synthesis of arylsulphates by particle-free mammalian liver preparations. It has already been pointed out3 that the type I arylsulphatase of mammalian livers (arylsulphatase C) cannot be directly involved in this synthetic process since the enzyme is microsomal in origin and highly insoluble. Similar considerations do not apply to the type II enzymes, however, since although they are mainly associated with the so-called ‘light mitochondria’, appreciable amounts are always present in preparations of the soluble components of the liver cell4.
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BAUM, H., DODGSON, K. Arylsulphate Synthesis and the Arylsulphatases. Nature 181, 115 (1958). https://doi.org/10.1038/181115a0
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DOI: https://doi.org/10.1038/181115a0
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