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A Histoautoradiographic Study of the Effect of Section of the Facial Nerve on the Uptake of Methionine-35S by the Cells of the Facial Nerve Nucleus

Nature volume 181, pages 341–342 (1958)Cite this article

Abstract

RETROGRADE degeneration of nerve cells was first described by Nissl in 18921. Its main features are swelling of the cells, breaking up of the cytoplasmic chromophile granules and displacement of the nucleus to the cell margin. These changes occur after a lesion in the axon, after excitation of long duration or after certain virus diseases, as, for example, poliomyelitis. It is still not known whether these changes are entirely degenerative in nature or are due to increased metabolic activity associated with increased synthesis of protein molecules. The biochemical processes underlying these changes have so far not been adequately explained. The results obtained from ultra-violet microspectrography of the nucleic acid content of these cells have not been entirely satisfactory2.

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References

  1. Nissl, F., Allg. Z. f. Physiol., 48, 197 (1892).

    Google Scholar 

  2. Hydén, H., “Neurochemistry”, 204 (Ch. C. Thomas, Springfield, Illinois, 1955).

    Google Scholar 

  3. Fischer, J., Koloušek, J., and Lodin, Z., Nature, 178, 1122 (1956).

    Article  ADS  CAS  Google Scholar 

  4. Cohn, P., Gaitonde, M. K., and Richter, D., J. Physiol., 126, 7P (1954).

    CAS  PubMed  Google Scholar 

  5. Koloušek, J., Fischer, J., and Lodin, Z., Cs. Morfologie, 4, 302 (1956); Acta Histochemica, 3, 328 (1956).

    Google Scholar 

  6. Bélanger, L. F., Anat. Rec., 107, 149 (1950).

    Article  Google Scholar 

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Authors and Affiliations

  1. Laboratory of Neuropathology, II, Institute of Pathological Anatomy of the Medical Faculty, Prague, II, U nemocnice 4

    J. FISCHER

  2. Czechoslovak Academy of Sciences, Institute of Physiology, Prague, 6, Na cvičišti 2, Czechoslovakia

    Z. LODIN & J. KOLOUŠEK

Authors
  1. J. FISCHER
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  2. Z. LODIN
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  3. J. KOLOUŠEK
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FISCHER, J., LODIN, Z. & KOLOUŠEK, J. A Histoautoradiographic Study of the Effect of Section of the Facial Nerve on the Uptake of Methionine-35S by the Cells of the Facial Nerve Nucleus. Nature 181, 341–342 (1958). https://doi.org/10.1038/181341a0

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