Abstract
DATA we have gathered concerning the mechanism by which X-rays block the biosynthesis of nucleic acid led us to postulate a hypothesis on the origin of X-induced mutations, which may also explain the spontaneous mutations.
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References
Errera, M., in Protoplasmatologia, “Handbuch der Protoplasmaforschung”, 10, 3 (Springer-Verlag, 1957).
Forssberg, A., and Klein, G., Exp. Cell. Res, 7, 480 (1954).
Bishop, C. W., and Davidson, J. N., Brit. J. Radiol., 30, 367 (1957).
Ord, M. G., and Stocken, L. A., Biochim. Biophys. Acta, 29, 201 (1958).
Grunberg-Manago, M., Ortiz, P. J., and Ochoa, S., Biochim. Biophys. Acta, 21, 197 (1956).
Adler, J., Lehman, I. R., Bessman, M. J., Simms, E. S., and Kornberg, A., Proc. U.S. Nat. Acad. Sci., 44, 641 (1958).
Lehman, I. R., Zimmerman, S. B., Adler, J., Bessman, M. J., Simms, E. S., and Kornberg, A., Proc. U.S. Nat. Acad. Sci., 44, 1191 (1958).
Bessman, M. J., Lehman, I. R., Simms, E. S., and Kornberg, A., J. Biol., Chem., 233, 171 (1958).
Hershey, A. D., Dixon, J., and Chase, M., J. Gen. Physiol., 36, 777 (1952–1953).
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MANDEL, P., CHAMBON, P. A New Approach to the Mechanism of Mutations. Nature 184, 1501–1502 (1959). https://doi.org/10.1038/1841501a0
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DOI: https://doi.org/10.1038/1841501a0
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