Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Tumourigenesis in Ovaries of Mice Transplanted to the Liver, Kidney and Adjacent Tissues

Abstract

OVARIAN tumours, though rare in normal mice, occur with high frequency under a variety of experimental conditions: low doses of total body X-radiation1, transplantation to the spleen2, application of 9:10-dimethyl–l:2-benzanthracene to nearby skin3 return to normal site after a short sojourn in the spleen4, in mice hereditarily deficient with respect to reproductive function5, and in ovaries transplanted to the testes of intact mice6.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Furth, J., and Butterworth, J. S., Amer. J. Cancer, 28, 66 (1936).

    Google Scholar 

  2. Li, M. H., and Gardner, W. U., Science, 105, 13 (1947).

    Article  ADS  CAS  Google Scholar 

  3. Howell, J. S., Marchant, J., and Orr, J. W., Brit. J. Cancer, 8, 635 (1954).

    Article  CAS  Google Scholar 

  4. Hummel, K. P., J. Nat. Cancer Inst., 15, 711 (1954).

    CAS  PubMed  Google Scholar 

  5. Russell, E. S., and Fekete, E., J. Nat. Cancer Inst., 21, 365 (1958).

    CAS  PubMed  Google Scholar 

  6. Gardner, W. U., Proc. Amer. Assoc. Cancer Res., 2, 300 (1958).

    Google Scholar 

  7. Guthrie, M. J., Cancer, 10, 190 (1957).

    Article  CAS  Google Scholar 

  8. Guthrie, M. J., Cancer, 11, 1226 (1958).

    Article  Google Scholar 

  9. Kirschbaum, A., Cancer Res., 17, 432 (1957).

    CAS  PubMed  Google Scholar 

  10. Fels, E., C. R. Soc. Biol., 149, 1666 (1955).

    CAS  Google Scholar 

  11. Allen, E., Hisaw, F. L., and Gardner, W. U., in “Sex and Internal Secretions”, edit. by Allen, E., 452(Williams and Wilkins Co., Baltimore, Md., 1939).

    Google Scholar 

  12. Little, C. C., J. Nat. Cancer Inst., 20, 441 (1958).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

GUTHRIE, M. Tumourigenesis in Ovaries of Mice Transplanted to the Liver, Kidney and Adjacent Tissues. Nature 184, 916–917 (1959). https://doi.org/10.1038/184916a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/184916a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing