Abstract
WORK on the mechanism of the radiation effect upon the synthesis of deoxyribonucleic acid in human bone marrow cells in vitro indicated a biphasic X-ray dose-response curve1. To test the applicability of these findings to other mammalian cell systems, similar work has been carried out with mouse Ehrlich ascites tumour cells; this system also has the advantage of being a more homogeneous cell population than bone marrow.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lajtha, L. G., Oliver, R., Berry, R., and Noyes, W. D., Nature, 182, 1788 (1958).
Lajtha, L. G., Oliver, R., Kumatori, T., and Ellis, F., Rad. Res., 8, 1 (1958).
Ord, M. G., and Stocken, L. A., Nature, 182, 1787 (1958).
Ebert, M., Hornsey, S., and Howard, A., Nature, 181, 613 (1958).
Deschner, E., and Gray, L. H., Rad. Res., 11, 115 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BERRY, R., HELL, E., LAJTHA, L. et al. Mechanism of the Radiation Effect on the Synthesis of Deoxyribonucleic Acid. Nature 186, 563–564 (1960). https://doi.org/10.1038/186563a0
Issue Date:
DOI: https://doi.org/10.1038/186563a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.