Abstract
RECENTLY, Douglas and Rubin1 have suggested that acetylcholine, the physiological transmitter of sympathetic nerve effects at the adrenal medulla, evokes catecholamine secretion by causing calcium ions to penetrate the medullary cells. Our experiments with calcium-45 have now provided further evidence consonant with this idea.
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Douglas, W. W., and Rubin, R. P., J. Physiol., 159, 24 P (1961); Biochem. Pharmacol., 8, 20 (1961). Douglas, W. W., and Rubin, R. P., J. Physiol., 159, 40 (1961).
Harris, E. J., Transport and Accumulation in Biological Systems, second ed. (Butterworths, London; Academic Press, New York, 1960).
Shanes, A. M., J. Cell. Comp. Physiol., 57, 193 (1960).
Rosenfeld, G., Amer. J. Physiol., 183, 272 (1955).
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DOUGLAS, W., POISNER, A. Stimulation of Uptake of Calcium-45 in the Adrenal Gland by Acetylcholine. Nature 192, 1299 (1961). https://doi.org/10.1038/1921299a0
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DOI: https://doi.org/10.1038/1921299a0
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Orientierende Übersicht
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