Abstract
ALTHOUGH at present many data are available concerning the production of citric acid by fungi1–5, very little is known of the mechanism by which the production of this acid is regulated. Its production in Aspergillus niger varies greatly with the strain and the medium6,7. The same strain, under various conditions, is capable in one case of converting practically all the sugar available into citric acid; in another case production is decreased by the conditions of the reaction practically to zero.
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FENCL, Z., VINTROVÁ, E. A New Metabolic Regulator : its Stimulation of Citric Acid Production and Anti-sulphon-amide and Streptomycin Effect. Nature 199, 905–906 (1963). https://doi.org/10.1038/199905a0
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DOI: https://doi.org/10.1038/199905a0
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