Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Changes in the Quantity and Nature of Collagen in Rabbit Skin as a Function of Age

Nature volume 207, pages 865–866 (1965)Cite this article

Abstract

THE process of ageing is known to be accompanied by changes in the chemistry of connective tissue. In general collagen seems to accumulate with increasing age. Nevertheless, this is only true for the insoluble fraction, since the soluble collagens, which represent the newly formed molecules, decrease with age, reflecting the lowered rate of synthesis. Most of the work in this connexion has been reviewed in detail by Harkness1.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Harkness, R. D., Biol. Rev., 36, 339 (1961).

    Article  Google Scholar 

  2. Nimni, M. E., and Bavetta, L. A., Proc. Soc. Exp. Biol. and Med., 117, 618 (1964).

    Article  CAS  Google Scholar 

  3. Bakerman, S., Nature, 196, 375 (1962).

    Article  ADS  CAS  Google Scholar 

  4. Woessner, jun., J. R., Arch. Biochem. Biophys., 93, 440 (1961).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry and Nutrition, School of Dentistry, University of Southern California, Los Angeles

    M. E. NIMNI, E. DE GUIA & L. A. BAVETTA

Authors
  1. M. E. NIMNI
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. DE GUIA
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. A. BAVETTA
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

NIMNI, M., DE GUIA, E. & BAVETTA, L. Changes in the Quantity and Nature of Collagen in Rabbit Skin as a Function of Age. Nature 207, 865–866 (1965). https://doi.org/10.1038/207865a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/207865a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing