Abstract
IN a recent article1 a technique was described for screening drug-sensitive strains of Enterobacteriaceae for the presence of transfer factors. This entails the incorporation of each strain under test in a mixture consisting of an intermediate recipient, containing a non-transferring resistance determinant (R-determinant)1,2 and a final recipient which is drug-sensitive and devoid of a transfer factor. If a test strain carries a transfer factor, this migrates into the intermediate recipient and unites with the R-determinant to form an R-factor which then transfers into the final recipient.
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References
Anderson, E. S., and Lewis, M. J., Nature, 208, 843 (1965).
Anderson, E. S., and Lewis, M. J., Nature, 206, 579 (1965).
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ANDERSON, E. A Rapid Screening Test for Transfer Factors in Drug-sensitive Enterobacteriaceae. Nature 208, 1016–1017 (1965). https://doi.org/10.1038/2081016a0
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DOI: https://doi.org/10.1038/2081016a0
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