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Effect of Calcium on Mitosis in the Thymuses of Normal and Irradiated Rats

Abstract

THE demonstration that increased levels of calcium in cultures of strain L mouse fibroblasts and rat thymocytes stimulated mitosis and reduced, or prevented, the transient mitotic delay produced by irradiation1,2 led to the hypothesis that a rise in the concentration of calcium in the blood and tissues might also stimulate normal mitosis and reduce post-irradiation mitotic delay in the whole animal.

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PERRIS, A., WHITFIELD, J. Effect of Calcium on Mitosis in the Thymuses of Normal and Irradiated Rats. Nature 214, 302–303 (1967). https://doi.org/10.1038/214302a0

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